Thank you everyone for the responses so far! Sorry for the delay in getting back to you. I've taken your advice into account and have put together the following parts. Let me know what you think!

LED and PCB:

- Nichia E21A 5000k mounted on a 16mm PCB from Virence

https://www.virence.com/product-page/vr16s1

- I also ordered a few other cheaper Nichia 219C mounted to a 16mm PCB to play around with while I'm experimenting

Driver:

https://www.ledsupply.com/led-drivers/buckpuck-dc-led-drivers

I'm thinking of going with this 500mA constant-current driver with built in potentiometer. The voltage range required (7-32v) should work well with 3x 18650 in series. Advantages I see here:

  • Simple UI, just on/off and brightness control
  • Ability to trim the output with the build in trim control if a full 500mA creates too much heat at the PCB
  • Easy to place inside housing
  • Easy to wire to other components with less critical soldering operations

Most people thought 3 batteries was overkill, but sometimes we have 12+ hour days, and I would like the light to be able to last for several days between charges. Also, the extra size and weight is less of a problem in a waist mounted battery pack.

Lens:

  • I ordered a variety of different 20mm Carclo TIR optics as well as a few 20mm convex lenses so I can try different configurations

Charger:

  • Here I need some help again. I would really like to include the ability to charge the batteries via micro USB instead of having to remove them every time. This way I could charge on any cell phone charger or from a computer USB if necessary. It would also make my enclosure design less critical - I can use screws instead of having to design a battery door or something for easy access.
  • I found this really nice little charger circuit, but it's obviously built to charge to 4.2v. Since I'm planning 3 batteries in series to run my driver, is there any way to include this or something like it? http://www.mtnelectronics.com/index.php?route=product/product&product_id=135
  • Here's another charger which seems to have flexible input and output. Would this be safe to use to charge 3 18650s in series using an old laptop charger? http://www.mtnelectronics.com/index.php?route=product/product&path=79&product_id=136

Other:

Phlogiston mentioned sterilization - this will not be a concern as the light does not have to be sterilized in any way. During surgery the only the region from the hips to the chest are considered sterile. We wear clean caps to keep hair out of the operating field and masks to prevent spreading bacteria from nose/mouth, but glasses, loupes, head lights, shoes, etc are not actually sterile. For this reason any buttons or control mounted to the light would not be helpful, so controls at the battery pack that can be adjusted through the sterile surgical gown are necessary.

Let me know if you have any more suggestions!