What I do when I’m too lazy to format / reinstall Windows AND the system is seriously infected :

  1. offline disinfection (boot your system with an antivirus boot CD or usb drive)
  2. boot system and run another stand-alone disinfection tool (DrWeb CureIt generally works OK for me)
  3. install a good AV

Basically a 2-stage disinfection.

If there’s still some malicious crap after that, then :person_facepalming:

Also all my personal computers run Linux :smiling_imp: