Triple is the most you can get in an S2+. For quad you would need to go bigger, like an M2. Here’s my quad 219B M2 with a custom kiriba-ru spacer:
3 amps per 219B is the max I go as long as it’s on a copper DTP board: Nichia 219B 4500k D220 9080 CRI Emitter output test by Texas_Ace; Amazing tint and CRI! Output is what you would expect.