Coronavirus **personal experiences** thread

[sb56637]

@sb56637

@pennzy

Isn’t the test for a vaccine if it produces antibodies without doing harm? But if antibodies don’t protect us ……Good one mother nature!

Yeah, it’s conceivable that a virus can either not allow for the production of antibodies or be impervious to them, I’m not sure what the technical explanation is, but HIV is a common example. But as I commented above, it’s practically certain that for this coronavirus neutralizing antibodies do get produced and they do work at least for a certain time, because that’s how tons of people have recovered from it.

Or maybe I’m totally wrong…
From jeff51’s article:

@technologyreview.com/2020/06/19/1004169/biggest-questions-about-immunity-to-covid-19

Those in this group who survived infection (typically younger people) likely had to fight off infection through cell-mediated arms of the immune system—white blood cells and cytokines that directly engage and kill pathogens—rather than through antibodies that neutralize the virus.

That’s not the first time I’ve heard of “cellular immunity” to this. So still tons of stuff that nobody knows for sure yet.

[xevious (Gary)]

@sb56637

@Lightbringer

Okay, I must be missing something…

So if developing antibodies from actual exposure to the actual plague doesn’t (or isn’t guaranteed to) work, how is getting vaccinated supposed to be better?

It sounds like it’s more of a question of the durability of the immunity. It’s pretty much guaranteed that neutralizing antibodies can be developed against this coronavirus, because otherwise nobody would have been able to recover from it. It’s only been a few short months since the first infected have recovered from it, so it will be informative to see what happens to them after 6 months or a year.

Vaccine → weakened/dead plague critters or parts thereof,.

RNA vaccines too that are supposed to give instructions to your cells to directly produce antibodies.

Definitely a ton of unknowns though.

Yes, I agree. Either the concentration of antibodies from survival of the virus is weak enough to perhaps be insufficient to fight off another infection, or the vaccine introduces a more robust version of the antibodies that can do a better job of it.

[Lightbringer]

@pennzy

Isn’t the test for a vaccine if it produces antibodies without doing harm? But if antibodies don’t protect us ……Good one mother nature!

Antibodies

[klrman]

@xevious

Thanks for the link, Jeff. This is aligned with what I’d been saying earlier–the only sure way to beat this virus is vaccination. And yes, everyone must get it. It’s really disheartening to hear about how anti-bodies doesn’t guarantee immunity from reinfection. This is NASTY beyond belief .

uh, ok. Why don't you get it first and tell us how it went. I'll check with you in 10-15 years to see if there were any side effects. Sometimes I wonder about you guys when you make statements like that.

[jon_slider]

@sb56637

Now, to play Devil’s advocate, there also exists a possibility or even likelihood that her first test was a false positive

the antibody tests are relatively accurate
it is the virus test that is unreliable
according to my Ph.D Cancer Biology daughter

the roommate went to New York in March and got sick for 2 weeks, then came home to California.

the antibody test in May, was the first confirmation that she had Corona, it was neither diagnosed nor tested for in March.

you can take it to the bank, until you develop new data, that this sample of one, indicates corona antibodies are extinguished in 3 months…

and the fact the antibodies were detected, pretty much negates the line of reasoning that people are overcoming Corona, without having any antibodies afterwards…

Occams razor
the simplest answer is closest to the truth

you get sick, you get antibodies, when the antibodies are gone, you are no longer immune

some things make you sick and you get antibodies that last a lifetime, some last 3 months, and for some, you remain a carrier for life, such as herpes…

corona at least, seems to clear the body… not like herpes, but also does not produce permanent antibodies… like measles does… or a polio vaccine…

just my thoughts… not meaning to argue, just brainstorm

[kennybobby]

+1 klr, when pressured and rushed to find an answer so the economy can get back to greater than its ever been, then accidents are bound to happen.

Got to get back to work to earn a living—but you won’t need money much if you ain’t living.

Job #1 is survival.

[MtnDon (Don Miller)]

@jon_slider

@sb56637

Now, to play Devil’s advocate, there also exists a possibility or even likelihood that her first test was a false positive

the antibody tests are relatively accurate
it is the virus test that is unreliable
according to my Ph.D Cancer Biology daughter

the roommate went to New York in March and got sick for 2 weeks, then came home to California.

the antibody test in May, was the first confirmation that she had Corona, it was neither diagnosed nor tested for in March.

you can take it to the bank, until you develop new data, that this sample of one, indicates corona antibodies are extinguished in 3 months…

and the fact the antibodies were detected, pretty much negates the line of reasoning that people are overcoming Corona, without having any antibodies afterwards…

Occams razor
the simplest answer is closest to the truth

you get sick, you get antibodies, when the antibodies are gone, you are no longer immune

some things make you sick and you get antibodies that last a lifetime, some last 3 months, and for some, you remain a carrier for life, such as herpes…

corona at least, seems to clear the body… not like herpes, but also does not produce permanent antibodies… like measles does… or a polio vaccine…

just my thoughts… not meaning to argue, just brainstorm

That sounds likely. Maybe not what we want to hear, but seems like a good chance to be true.

[Rexlion]

@Lightbringer

Okay, I must be missing something…

So if developing antibodies from actual exposure to the actual plague doesn’t (or isn’t guaranteed to) work, how is getting vaccinated supposed to be better?

Actual exposure → real plague critters, fight ’em off, develop antibodies, fight off future infections [without getting sick].

Vaccine → weakened/dead plague critters or parts thereof, develop antibodies, fight off future infections [without getting sick].

It’s quite simple, really. They’ll inject us with nanobots that rewrite our DNA to be immune to Coronaviruses. Problem solved! :partying_face: (If you don’t mind having your DNA altered, that is.) :nerd_face:

[Lightbringer]

I’ll stick with silver…

[jon_slider]

estimates derived from confirmed cases plus antibody testing results, suggest the actual infection rate is 12x the confirmed number

by those measures
1 out of 10 people in USA has had corona
1 out of 2400 people in USA has died from corona

[pennzy]

The 60s and 70s already altered my DNA.

[hank]

Here’s an update on vaccination trials:

Coronavirus Vaccine Update, June 29 - SoylentNews

The info comes from:
https://blogs.sciencemag.org/pipeline/archives/2020/06/29/coronavirus-vaccine-update-june-29

[Rexlion]

140,000 is four one-hundredths of one percent of the US population (0.04%), btw.

[xevious (Gary)]

@klrman

@xevious

Thanks for the link, Jeff. This is aligned with what I’d been saying earlier—the only sure way to beat this virus is vaccination. And yes, everyone must get it. It’s really disheartening to hear about how anti-bodies doesn’t guarantee immunity from reinfection. This is NASTY beyond belief .

uh, ok. Why don’t you get it first and tell  us how it went. I’ll check with you in 10-15 years to see if there were any side effects. Sometimes I wonder about you guys when you make statements like that.

Do I really have to qualify this? :person_facepalming: One might expect this to be obvious. The “qualified” vaccine, FDA certified safe. You know, like getting a shot for tetanus or polio. You don’t need to do it in order to survive, but it’s an extremely good idea to do it in case you get unlucky.

[hank]

One item from the Sciencemag news article
https://blogs.sciencemag.org/pipeline/archives/2020/06/29/coronavirus-va…
on various vaccines in trial currently, this one is interesting:

Vaxart: Now, these folks I had not heard much until the other day, when they popped up with a surprise press release saying that their vaccine candidate had been selected as part of the government’s “Operation Warp Speed”
https://investors.vaxart.com/news-releases/news-release-details/vaxarts-covid-19-vaccine-selected-us-governments-operation-warp
for a challenge test in primates. They have a platform developing oral vaccines – an adenovirus vector delivered in a coated tablet to get past the stomach and into the small intestine. (There’s an immediately obvious difference this route and the injectables in ease of storage and administration, which might be quite advantageous). This “mucosal immunity” technique will be familiar to many via its use in the oral polio vaccine, and the differences between it and the immune response generated by injection are quite complex. Vaxart hopes to go into Phase I later this year,…

Yeah, I can’t say I trust my government — when “Operation Warp Speed” comes out with a vaccine and starts promoting it, right before Election Day, I will be suspicious about what’s being politically warped and what’s speedy.

But eventually I expect trustworthy results from the science community.

[pennzy]

This theory says the virus was already everywhere lying dormant and was triggered when conditions were right.

Exclusive: Covid-19 may not have originated in China, Oxford University...

[xevious (Gary)]

@pennzy

This theory says the virus was already everywhere lying dormant and was triggered when conditions were right.
Exclusive: Covid-19 may not have originated in China, Oxford University expert believes

Don’t know about that… a bit hard to believe considering all the factors. Viruses “evolve” over time, with mutations. It would be really interesting to find the “cousin” to COVID-19… and see what factor caused the mutation for it to be well suited to human hosts, as well as bring about the devastating contagious capability (as well as lingering chronic symptoms for some people).

[Lightbringer]

@xevious

Don’t know about that… a bit hard to believe considering all the factors. Viruses “evolve” over time, with mutations. It would be really interesting to find the “cousin” to COVID-19… and see what factor caused the mutation for it to be well suited to human hosts, as well as bring about the devastating contagious capability (as well as lingering chronic symptoms for some people).

You know the reason…

They won’t have to fire a shot.

[xevious (Gary)]

^

[Thunderay]

COVID-19 Vaccine: Big Pharma Rushing to Make It